KIF4A

Across TCGA patient cohorts, KIF4A protein abundance is significantly associated with the protein abundance of many other proteins, with 28,062 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible KIF4A-associated proteins across cancer lineages are KIF20A, KIF23, and DHFR. Each is linked with KIF4A in more than 7 cancer types. Because this analysis shows association rather than direction, both KIF4A-to-partner and partner-to-KIF4A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF4A versus KIF20A in BRCA, with a Pearson correlation of 0.77.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF4A→partner) and Y-score (partner→KIF4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KIF20A →	+0.774	+0.725	<.001	<.001	3	8
LUAD	KIF23 →	+1.094	+0.894	<.001	<.001	3	8
LUAD	DHFR →	+0.704	+0.637	<.001	<.001	3	8
LSCC	DNMT1 →	+0.438	+0.613	<.001	<.001	3	8
UCEC	TK1 →	+0.867	+0.933	<.001	<.001	3	8
LUAD	TPX2 →	+1.128	+0.949	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 28,062 associations by consensus.

KIF4A vs KIF20A — BRCA

Explore this scatter interactively →