KIF3C

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIF3C protein abundance is significantly associated with the RNA expression of many other genes, with 4,474 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KIF3C-associated genes across cancer lineages are TCFL5, SCG5, and SDC4. Each is linked with KIF3C in more than 2 cancer types. Because this analysis shows association rather than direction, both KIF3C-to-partner and partner-to-KIF3C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF3C versus TCFL5 in GBM, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF3C→partner) and Y-score (partner→KIF3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMTCFL5 →+0.774+0.438<.001<.00133
LUADSCG5 →+1.821+0.491.003.00133
OVSDC4 →-1.156-0.632<.001<.00132
OVCPLX2 →+1.926+0.401.004<.00132
GBMNODAL →+0.503+0.304.001<.00132
OVFBP1 →-1.687-0.554.002<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,474 associations by consensus.

KIF3C vs TCFL5 — GBM

Per-sample scatter of KIF3C vs TCFL5 in GBM (Pearson r = 0.41).

Explore this scatter interactively →

Exploration