KIF3C

Across TCGA cell cohorts, KIF3C RNA expression is significantly associated with the go_rna of many other GO terms, with 5,377 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIF3C-associated GO terms across cancer lineages are Actin filament depolymerization, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, and Retrograde transport, endosome to Golgi. Each is linked with KIF3C in more than 14 cancer types. Because this analysis shows association rather than direction, both KIF3C-to-partner and partner-to-KIF3C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin filament depolymerization grouped by KIF3C-low versus KIF3C-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF3C→partner) and Y-score (partner→KIF3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Actin filament depolymerization →	+0.203	+1.812	<.001	.001	3	14
STOMACH	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process →	+0.045	+1.469	<.001	<.001	3	14
OESOPHAGUS	Retrograde transport, endosome to Golgi →	+0.084	+1.523	.001	<.001	3	14
SKIN	Glucose catabolic process →	+0.130	+1.517	<.001	<.001	3	14
URINARY_TRACT	Protein depolymerization →	+0.141	+1.597	<.001	.004	2	15
OESOPHAGUS	Endosomal transport →	+0.070	+1.771	.006	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,377 associations by consensus.

Actin filament depolymerization by KIF3C expression — URINARY_TRACT

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