KIF26B

Across TCGA patient cohorts, KIF26B mutation is significantly associated with the RNA expression of many other genes, with 10,500 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF26B-associated genes across cancer lineages are TRMU, HELLS, and CEP131. Each is linked with KIF26B in more than 5 cancer types. Because this analysis shows association rather than direction, both KIF26B-to-partner and partner-to-KIF26B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRMU grouped by KIF26B-low versus KIF26B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF26B→partner) and Y-score (partner→KIF26B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRMU →	+0.509	+2.025	<.001	<.001	3	6
UCEC	HELLS →	+0.728	+1.921	<.001	<.001	3	6
UCEC	CEP131 →	+0.235	+1.798	.006	.001	3	6
UCEC	LETM1 →	+0.490	+2.200	<.001	<.001	3	5
UCEC	XPNPEP1 →	+0.520	+2.025	<.001	<.001	3	5
UCEC	PSMD9 →	+0.397	+1.667	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,500 associations by consensus.

TRMU by KIF26B expression — UCEC

Explore this box plot interactively →