KIF26B

Across TCGA pan-cancer cohorts, KIF26B RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated KIF26B data layer compared with 14 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher KIF26B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KIF26B expression acts as an unfavorable survival marker, although some lineages such as SCLC and LUAD show a favorable association.

MESO, OV, and ACC are the cancer types where KIF26B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	All	0.392	0.711	<.001	90	view →
OV	OS	Quartile	All	0.332	0.465	.003	64	view →
ACC	DFS	Median	All	0.428	0.732	<.001	48	view →
LGG	OS	Median	All	0.841	0.947	<.001	35	view →
THCA	OS	Tertile	All	0.975	1.000	.003	33	view →
SCLC	DFS	Median	All	0.738	0.500	.003	27	view →
LUAD	DFS	Quartile	II,III,IV	0.606	0.298	.007	20	view →
CESC	DFS	Tertile	All	0.772	0.876	.012	18	view →
COAD	DFS	Tertile	All	0.695	0.829	.009	17	view →
KICH	DFS	Quartile	II,III,IV	0.491	1.000	.002	16	view →
UVM	DFS	Tertile	III,IV	0.338	0.782	.006	15	view →
HNSC	DFS	Quartile	All	0.534	0.727	.018	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

KIF26B–MESO (OS)

Open the MESO breakdown →