KIF26B

Across TCGA cell cohorts, KIF26B mutation is significantly associated with the RNA expression of many other genes, with 1,013 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIF26B-associated genes across cancer lineages are SLC13A1, ZIC3, and NEK4. Each is linked with KIF26B in more than 2 cancer types. Because this analysis shows association rather than direction, both KIF26B-to-partner and partner-to-KIF26B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC13A1 grouped by KIF26B-low versus KIF26B-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF26B→partner) and Y-score (partner→KIF26B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	SLC13A1 →	+0.018	+2.925	.008	.002	3	3
BLOOD_Leukemia	ZIC3 →	+0.007	+2.668	<.001	.005	3	3
LARGE_INTESTINE	NEK4 →	+0.529	+2.459	.001	.003	3	3
LARGE_INTESTINE	PLCL2 →	+0.792	+2.160	<.001	.001	3	3
BLOOD_Lymphoma	SLAMF9 →	+0.119	+2.977	.003	.002	3	2
BLOOD_Lymphoma	TSPAN19 →	+0.382	+3.678	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,013 associations by consensus.

SLC13A1 by KIF26B expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →