KIF1C

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KIF1C RNA expression is significantly associated with the go_rna of many other GO terms, with 4,559 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KIF1C-associated GO terms across cancer lineages are Anterograde neuronal dense core vesicle transport, Mitotic centrosome separation, and Retrograde axonal transport. Each is linked with KIF1C in more than 18 cancer types. Because this analysis shows association rather than direction, both KIF1C-to-partner and partner-to-KIF1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Anterograde neuronal dense core vesicle transport grouped by KIF1C-low versus KIF1C-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF1C→partner) and Y-score (partner→KIF1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEAnterograde neuronal dense core vesicle transport →+0.229+1.136<.001<.001319
BREASTMitotic centrosome separation →+0.116+0.715<.001.002313
BREASTRetrograde axonal transport →+0.138+1.197.004<.001313
BONECytosolic transport →+0.085+1.481<.001<.001313
SKINRetrograde transport, endosome to Golgi →+0.070+1.040<.001<.001313
BONEPhosphatidylinositol biosynthetic process →+0.059+1.188<.001.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,559 associations by consensus.

Anterograde neuronal dense core vesicle transport by KIF1C expression — BONE

Box plot of Anterograde neuronal dense core vesicle transport in KIF1C-low vs KIF1C-high samples in BONE.

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Exploration