KIF1C

Across TCGA cell cohorts, KIF1C mutation is significantly associated with the mutation status of many other genes, with 5,404 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIF1C-associated genes across cancer lineages are PTPRF, BRPF1, and DPP3. Each is linked with KIF1C in more than 4 cancer types. Because this analysis shows association rather than direction, both KIF1C-to-partner and partner-to-KIF1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTPRF grouped by KIF1C-low versus KIF1C-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF1C→partner) and Y-score (partner→KIF1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PTPRF →	+3.847	+5.108	.001	.001	1	5
BLOOD_Leukemia	BRPF1 →	+3.662	+3.285	.004	.004	1	5
UPPER_AERODIGESTIVE_TRACT	DPP3 →	+4.392	+4.954	.008	.008	1	5
LARGE_INTESTINE	SLC38A10 →	+2.793	+2.544	.003	.003	1	5
LARGE_INTESTINE	HERC1 →	+1.833	+3.261	<.001	<.001	1	5
LARGE_INTESTINE	RPAP1 →	+2.471	+2.857	<.001	<.001	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,404 associations by consensus.

PTPRF by KIF1C expression — BLOOD_Lymphoma

Explore this box plot interactively →