KIF1A

Across TCGA patient cohorts, KIF1A protein abundance is significantly associated with the RNA expression of many other genes, with 11,917 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KIF1A-associated genes across cancer lineages are KIF3C, TMOD2, and SEPTIN3. Each is linked with KIF1A in more than 4 cancer types. Because this analysis shows association rather than direction, both KIF1A-to-partner and partner-to-KIF1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF1A versus KIF3C in BRCA, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF1A→partner) and Y-score (partner→KIF1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KIF3C →	+0.886	+0.896	<.001	<.001	3	5
HNSC	TMOD2 →	+0.942	+1.055	<.001	.007	3	4
GBM	SEPTIN3 →	+1.152	+0.467	<.001	<.001	3	4
GBM	TUBB4A →	+2.107	+0.592	<.001	<.001	3	4
LSCC	MPP2 →	+0.765	+1.016	<.001	<.001	3	4
GBM	RIMS3 →	+1.345	+0.494	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,917 associations by consensus.

KIF1A vs KIF3C — BRCA

Explore this scatter interactively →