KIF18A

Across TCGA patient cohorts, KIF18A protein abundance is significantly associated with the RNA expression of many other genes, with 7,700 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KIF18A-associated genes across cancer lineages are BARD1, RPS3AP3, and GJA5. Each is linked with KIF18A in more than 1 cancer types. Because this analysis shows association rather than direction, both KIF18A-to-partner and partner-to-KIF18A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF18A versus BARD1 in LSCC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF18A→partner) and Y-score (partner→KIF18A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	BARD1 →	+0.815	+0.817	<.001	<.001	3	2
GBM	RPS3AP3 →	+0.811	+0.999	.009	.008	3	2
LSCC	GJA5 →	-0.689	-0.441	.002	.004	3	2
HNSC	CKS2 →	+1.601	+0.739	.001	.006	3	2
HNSC	TOP2A →	+1.921	+0.783	<.001	.002	3	2
LSCC	KIF20B →	+0.645	+0.620	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,700 associations by consensus.

KIF18A vs BARD1 — LSCC

Explore this scatter interactively →