KIF17

Across TCGA patient cohorts, KIF17 mutation is significantly associated with the total protein of many other genes, with 59 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF17-associated genes across cancer lineages are ASNS, C-Raf, and FASN. Each is linked with KIF17 in more than 3 cancer types. Because this analysis shows association rather than direction, both KIF17-to-partner and partner-to-KIF17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by KIF17-low versus KIF17-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF17→partner) and Y-score (partner→KIF17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ASNS →	+0.454	+2.230	.002	.006	3	4
UCEC	C-Raf →	+0.131	+2.321	.003	<.001	3	4
STAD	FASN →	+0.373	+2.321	.047	.034	3	3
STAD	c-Kit →	-0.378	-3.169	.007	.018	3	3
STAD	53BP1 →	+0.473	+2.321	.007	.034	3	3
UCEC	Mre11 →	-0.063	-1.201	.017	.028	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

ASNS by KIF17 expression — COAD

Explore this box plot interactively →