KIF17

Across TCGA cell cohorts, KIF17 mutation is significantly associated with the RNA expression of many other genes, with 822 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIF17-associated genes across cancer lineages are OR6V1, OR9A2, and OIP5. Each is linked with KIF17 in more than 2 cancer types. Because this analysis shows association rather than direction, both KIF17-to-partner and partner-to-KIF17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6V1 grouped by KIF17-low versus KIF17-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF17→partner) and Y-score (partner→KIF17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR6V1 →	+0.010	+3.189	.002	.007	3	3
BLOOD_Leukemia	OR9A2 →	+0.020	+2.133	.001	.008	3	3
LARGE_INTESTINE	OIP5 →	+0.782	+3.364	<.001	.002	3	2
LARGE_INTESTINE	GLIPR2 →	+1.106	+3.364	.002	.002	3	2
LARGE_INTESTINE	ATG4C →	+0.676	+3.364	<.001	.002	3	2
BLOOD_Leukemia	BBS7 →	+0.754	+3.489	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 822 associations by consensus.

OR6V1 by KIF17 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →