KIF15

Across TCGA cell cohorts, KIF15 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,077 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIF15-associated GO terms across cancer lineages are Sister chromatid segregation, Attachment of spindle microtubules to kinetochore, and Mitotic spindle assembly. Each is linked with KIF15 in more than 19 cancer types. Because this analysis shows association rather than direction, both KIF15-to-partner and partner-to-KIF15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sister chromatid segregation grouped by KIF15-low versus KIF15-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF15→partner) and Y-score (partner→KIF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Sister chromatid segregation →	+0.102	+0.788	<.001	.004	3	20
URINARY_TRACT	Attachment of spindle microtubules to kinetochore →	+0.157	+1.206	<.001	<.001	3	20
BONE	Mitotic spindle assembly →	+0.155	+1.572	<.001	.001	3	20
URINARY_TRACT	Regulation of G2/M transition of mitotic cell cycle →	+0.101	+1.268	<.001	<.001	3	19
OESOPHAGUS	Meiotic nuclear division →	+0.094	+1.305	.002	.004	3	19
URINARY_TRACT	Regulation of cell cycle G2/M phase transition →	+0.088	+1.177	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,077 associations by consensus.

Sister chromatid segregation by KIF15 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →