KIF14

Across TCGA cell cohorts, KIF14 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,672 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIF14-associated GO terms across cancer lineages are Regulation of G2/M transition of mitotic cell cycle, Mitotic nuclear division, and Regulation of cell cycle G2/M phase transition. Each is linked with KIF14 in more than 19 cancer types. Because this analysis shows association rather than direction, both KIF14-to-partner and partner-to-KIF14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of G2/M transition of mitotic cell cycle grouped by KIF14-low versus KIF14-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF14→partner) and Y-score (partner→KIF14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of G2/M transition of mitotic cell cycle →	+0.097	+1.320	<.001	<.001	3	20
OESOPHAGUS	Mitotic nuclear division →	+0.120	+0.895	<.001	<.001	3	20
OVARY	Regulation of cell cycle G2/M phase transition →	+0.086	+1.197	<.001	<.001	3	20
BONE	Microtubule cytoskeleton organization involved in mitosis →	+0.113	+1.253	<.001	<.001	3	20
SOFT_TISSUE	Positive regulation of chromosome condensation →	+0.267	+1.535	<.001	<.001	3	20
OESOPHAGUS	Nuclear division →	+0.091	+0.882	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,672 associations by consensus.

Regulation of G2/M transition of mitotic cell cycle by KIF14 expression — OVARY

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