KIF14

Across TCGA cell cohorts, KIF14 mutation is significantly associated with the RNA expression of many other genes, with 130 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIF14-associated genes across cancer lineages are MS4A15, ALOXE3, and TPPP2. Each is linked with KIF14 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIF14-to-partner and partner-to-KIF14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A15 grouped by KIF14-low versus KIF14-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF14→partner) and Y-score (partner→KIF14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MS4A15 →	+0.079	+2.857	.002	<.001	3	2
BLOOD_Leukemia	ALOXE3 →	+0.225	+2.232	<.001	.008	3	2
SKIN	TPPP2 →	+0.058	+3.632	<.001	.003	3	2
BLOOD_Myeloma	CT47A6 →	+0.586	+4.807	<.001	.006	3	1
LUNG_NSCLC_LUSC	AQP12A →	+0.042	+4.108	.005	.005	3	1
BLOOD_Leukemia	APOBEC3H →	+1.528	+3.584	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 130 associations by consensus.

MS4A15 by KIF14 expression — BLOOD_Leukemia

Explore this box plot interactively →