KIAA1549L

Across TCGA patient cohorts, KIAA1549L mutation is significantly associated with the total protein of many other genes, with 74 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1549L-associated genes across cancer lineages are GAPDH, mTOR_pS2448, and PDK1_pS241. Each is linked with KIAA1549L in more than 4 cancer types. Because this analysis shows association rather than direction, both KIAA1549L-to-partner and partner-to-KIAA1549L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by KIAA1549L-low versus KIAA1549L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1549L→partner) and Y-score (partner→KIAA1549L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.315	+1.000	.025	.020	3	5
COAD	mTOR_pS2448 →	-0.161	-3.152	.011	.017	3	4
LUAD	PDK1_pS241 →	-0.146	-1.568	.031	.035	3	4
STAD	ASNS →	+0.522	+2.459	.006	.019	3	4
UCEC	4E-BP1 →	+0.293	+2.137	<.001	<.001	3	4
LUAD	Cyclin-E2 →	+0.117	+1.999	.020	.029	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 74 associations by consensus.

GAPDH by KIAA1549L expression — UCEC

Explore this box plot interactively →