KIAA1549L

Across TCGA pan-cancer cohorts, KIAA1549L RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated KIAA1549L data layer compared with 11 for mutation status.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher KIAA1549L RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KIAA1549L expression acts as an unfavorable survival marker, although some lineages such as UVM and LGG show a favorable association.

STAD, MESO, and UVM are the cancer types where KIAA1549L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Quartile	II,III,IV	0.333	0.546	.003	98	view →
MESO	OS	Tertile	All	0.249	0.523	<.001	84	view →
UVM	OS	Median	All	0.804	0.424	<.001	79	view →
LGG	DFS	Median	All	0.801	0.669	<.001	46	view →
LUAD	DFS	Median	All	0.599	0.744	.007	44	view →
UCEC	OS	Median	All	0.829	0.915	<.001	40	view →
PAAD	DFS	Median	II,III,IV	0.352	0.572	.003	28	view →
SARC	DFS	Quartile	All	0.239	0.445	<.001	20	view →
LIHC	OS	Median	II,III,IV	0.681	0.291	.002	18	view →
COAD	DFS	Tertile	IV	0.321	0.702	.016	13	view →
ESCA	OS	Median	IV	0.698	0.222	.006	12	view →
BLCA	DFS	Quartile	All	0.432	0.574	.020	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

KIAA1549L–STAD (DFS)

Open the STAD breakdown →