KIAA1549L

Across TCGA cell cohorts, KIAA1549L mutation is significantly associated with the RNA expression of many other genes, with 1,189 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA1549L-associated genes across cancer lineages are BUB3, KIF27, and PHF5A. Each is linked with KIAA1549L in more than 2 cancer types. Because this analysis shows association rather than direction, both KIAA1549L-to-partner and partner-to-KIAA1549L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BUB3 grouped by KIAA1549L-low versus KIAA1549L-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1549L→partner) and Y-score (partner→KIAA1549L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BUB3 →	+0.371	+2.526	.007	.002	3	3
BLOOD_Leukemia	KIF27 →	+0.716	+3.351	.002	.003	3	3
LARGE_INTESTINE	PHF5A →	+0.546	+2.364	<.001	<.001	3	2
LARGE_INTESTINE	METTL4 →	+0.606	+2.364	<.001	<.001	3	2
LARGE_INTESTINE	CEP76 →	+0.658	+3.459	<.001	<.001	3	2
LARGE_INTESTINE	HOXA2 →	-0.636	-3.169	.006	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,189 associations by consensus.

BUB3 by KIAA1549L expression — LARGE_INTESTINE

Explore this box plot interactively →