KIAA1549

Across TCGA patient cohorts, KIAA1549 mutation is significantly associated with the RNA expression of many other genes, with 8,086 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1549-associated genes across cancer lineages are C1orf174, OXSR1, and RER1. Each is linked with KIAA1549 in more than 4 cancer types. Because this analysis shows association rather than direction, both KIAA1549-to-partner and partner-to-KIAA1549 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1orf174 grouped by KIAA1549-low versus KIAA1549-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1549→partner) and Y-score (partner→KIAA1549) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C1orf174 →	+0.503	+2.180	<.001	<.001	3	5
UCEC	OXSR1 →	+0.365	+2.269	<.001	<.001	3	5
COAD	RER1 →	+0.298	+2.186	<.001	.009	3	5
COAD	AP3S1 →	+0.502	+3.874	<.001	<.001	3	5
UCEC	LRRC47 →	+0.366	+3.434	<.001	<.001	3	5
UCEC	TAF9 →	+0.611	+2.662	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,086 associations by consensus.

C1orf174 by KIAA1549 expression — UCEC

Explore this box plot interactively →