KIAA1549

Across TCGA cell cohorts, KIAA1549 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,366 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KIAA1549-associated GO terms across cancer lineages are Positive regulation of gene expression, epigenetic, Positive regulation of double-strand break repair, and RNA export from nucleus. Each is linked with KIAA1549 in more than 12 cancer types. Because this analysis shows association rather than direction, both KIAA1549-to-partner and partner-to-KIAA1549 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of gene expression, epigenetic grouped by KIAA1549-low versus KIAA1549-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1549→partner) and Y-score (partner→KIAA1549) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of gene expression, epigenetic →	+0.074	+1.320	.002	<.001	3	13
PANCREAS	Positive regulation of double-strand break repair →	+0.067	+1.086	<.001	<.001	3	13
SOFT_TISSUE	RNA export from nucleus →	+0.125	+1.438	<.001	<.001	3	13
LUNG_SCLC	Transcription initiation-coupled chromatin remodeling →	+0.081	+1.392	.001	<.001	3	12
SOFT_TISSUE	Positive regulation of DNA repair →	+0.060	+0.897	<.001	<.001	3	12
LARGE_INTESTINE	Regulation of DNA repair →	+0.056	+1.119	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,366 associations by consensus.

Positive regulation of gene expression, epigenetic by KIAA1549 expression — LUNG_SCLC

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