KIAA1549

Across TCGA cell cohorts, KIAA1549 mutation is significantly associated with the RNA expression of many other genes, with 1,978 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA1549-associated genes across cancer lineages are ANKRD13B, CD2BP2, and DDHD1. Each is linked with KIAA1549 in more than 3 cancer types. Because this analysis shows association rather than direction, both KIAA1549-to-partner and partner-to-KIAA1549 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANKRD13B grouped by KIAA1549-low versus KIAA1549-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1549→partner) and Y-score (partner→KIAA1549) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ANKRD13B →	+0.872	+3.404	<.001	<.001	3	4
BLOOD_Leukemia	CD2BP2 →	+0.479	+2.489	.003	.007	3	3
LARGE_INTESTINE	DDHD1 →	+0.805	+1.780	<.001	<.001	3	3
SKIN	SLC45A1 →	+0.524	+3.131	.001	.008	3	3
LARGE_INTESTINE	AOC3 →	+0.417	+1.483	.003	.002	3	3
LARGE_INTESTINE	RPA1 →	+0.547	+1.780	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,978 associations by consensus.

ANKRD13B by KIAA1549 expression — LARGE_INTESTINE

Explore this box plot interactively →