KIAA1191

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIAA1191 mutation is significantly associated with the RNA expression of many other genes, with 1,075 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1191-associated genes across cancer lineages are RNU6-1308P, MIR4265, and LINC02647. Each is linked with KIAA1191 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA1191-to-partner and partner-to-KIAA1191 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1308P grouped by KIAA1191-low versus KIAA1191-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1191→partner) and Y-score (partner→KIAA1191) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADRNU6-1308P →+0.192+7.930<.001.00832
COADMIR4265 →+0.445+5.122.005.00432
SKCMLINC02647 →+0.124+7.816<.001.00831
BRCAVCY1B →+0.068+7.731.001.00931
BRCAVCY →+0.134+8.471<.001.00531
BRCARNU6-349P →+0.517+8.055<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,075 associations by consensus.

RNU6-1308P by KIAA1191 expression — LUAD

Box plot of RNU6-1308P in KIAA1191-low vs KIAA1191-high samples in LUAD.

Explore this box plot interactively →

Exploration