KIAA1191

Across TCGA pan-cancer cohorts, KIAA1191 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of KIAA1191’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where KIAA1191 RNA is repressed in tumor relative to normal tissue. In most cancer types KIAA1191 is over-expressed in tumor, although a few such as KIRP and LUSC show the opposite, repressed pattern.

KIRP, LUSC, and LIHC are the cancer types where KIAA1191 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIAA1191 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	All	−0.921	<.001	9	view →
LUSC	All	All	−0.306	<.001	7	view →
LIHC	Female	III,IV	+0.562	<.001	4	view →
CHOL	Female	All	+1.626	<.001	3	view →
KICH	All	All	−0.561	.005	3	view →
THCA	All	IV	−0.535	.015	3	view →
BLCA	Male	IV	−0.409	<.001	1	view →
LUAD	Female	II,III,IV	−0.244	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

KIAA1191–KIRP

Open the KIRP breakdown →