KIAA1109

Across TCGA patient cohorts, KIAA1109 protein abundance is significantly associated with the RNA expression of many other genes, with 6,848 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KIAA1109-associated genes across cancer lineages are NCAPH, KNTC1, and SPAG5. Each is linked with KIAA1109 in more than 3 cancer types. Because this analysis shows association rather than direction, both KIAA1109-to-partner and partner-to-KIAA1109 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIAA1109 versus NCAPH in UCEC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1109→partner) and Y-score (partner→KIAA1109) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NCAPH →	-0.666	-0.323	<.001	<.001	3	4
GBM	KNTC1 →	-0.708	-0.257	<.001	<.001	3	4
UCEC	SPAG5 →	-0.875	-0.248	<.001	.005	3	4
UCEC	POLR1E →	-0.691	-0.238	.001	.006	3	4
HNSC	GPATCH4 →	-0.580	-0.419	.001	.003	3	4
UCEC	RAD51AP1 →	-0.813	-0.344	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,848 associations by consensus.

KIAA1109 vs NCAPH — UCEC

Explore this scatter interactively →