KIAA1109

Across TCGA patient cohorts, KIAA1109 mutation is significantly associated with the RNA expression of many other genes, with 7,415 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1109-associated genes across cancer lineages are CXCL9, ZFYVE19, and PSMA6. Each is linked with KIAA1109 in more than 4 cancer types. Because this analysis shows association rather than direction, both KIAA1109-to-partner and partner-to-KIAA1109 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CXCL9 grouped by KIAA1109-low versus KIAA1109-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1109→partner) and Y-score (partner→KIAA1109) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CXCL9 →	+1.812	+2.075	<.001	<.001	3	5
SKCM	ZFYVE19 →	+0.324	+1.629	<.001	<.001	3	5
STAD	PSMA6 →	+0.411	+3.086	<.001	<.001	3	5
UCEC	MINDY4 →	-0.273	-1.286	<.001	<.001	3	5
UCEC	CDT1 →	+0.656	+1.539	<.001	<.001	3	5
UCEC	KIF11 →	+0.439	+1.163	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,415 associations by consensus.

CXCL9 by KIAA1109 expression — UCEC

Explore this box plot interactively →