KIAA0753

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIAA0753 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA0753-associated genes across cancer lineages are INPP4B, PDCD4, and Rab25. Each is linked with KIAA0753 in more than 2 cancer types. Because this analysis shows association rather than direction, both KIAA0753-to-partner and partner-to-KIAA0753 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0753→partner) and Y-score (partner→KIAA0753) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECINPP4B →-0.249-1.906.014.01432
UCECPDCD4 →-0.456-1.353.002.01532
UCECRab25 →-0.322-1.584.002.03232
UCECRad50 →-0.183-1.353.016.01532
COADATM →-0.681-3.169<.001.01732
COAD4E-BP1 →+0.326+3.169.001.01823
Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

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