Across TCGA cell cohorts, KIAA0753 mutation is significantly associated with the RNA expression of many other genes, with 639 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA0753-associated genes across cancer lineages are TEX53, RGPD4, and TRMU. Each is linked with KIAA0753 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA0753-to-partner and partner-to-KIAA0753 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0753→partner) and Y-score (partner→KIAA0753) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	TEX53 →	+0.105	+2.864	<.001	.009	3	2
BLOOD_Leukemia	RGPD4 →	+0.272	+3.658	<.001	.005	3	2
LARGE_INTESTINE	TRMU →	+0.619	+2.502	<.001	.005	3	2
LARGE_INTESTINE	OSBP →	+0.563	+2.502	.004	.005	3	2
LARGE_INTESTINE	BCL7A →	+0.754	+3.321	.003	.003	3	2
LARGE_INTESTINE	DCLRE1B →	+0.564	+3.628	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 639 associations by consensus.

Exploration

KIAA0753 survival (RNA) · tumor vs normal (RNA) · all KIAA0753 data types