KIAA0040

Across TCGA patient cohorts, KIAA0040 mutation is significantly associated with the RNA expression of many other genes, with 78 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA0040-associated genes across cancer lineages are TTTY7B, MIR548AP, and CCR8. Each is linked with KIAA0040 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA0040-to-partner and partner-to-KIAA0040 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TTTY7B grouped by KIAA0040-low versus KIAA0040-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0040→partner) and Y-score (partner→KIAA0040) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TTTY7B →	+0.024	+8.471	<.001	.005	3	1
BRCA	MIR548AP →	+0.322	+8.055	<.001	.007	3	1
UCEC	CCR8 →	+0.524	+3.223	.005	.009	3	1
UCEC	RNU6-235P →	+0.238	+3.198	.002	.007	3	1
UCEC	RNY4P3 →	+0.328	+2.833	.006	.006	3	1
UCEC	TMEM244 →	+0.215	+2.448	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 78 associations by consensus.

TTTY7B by KIAA0040 expression — BRCA

Explore this box plot interactively →