KIAA0040

Across TCGA patient cohorts, KIAA0040 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA0040-associated genes across cancer lineages are GAPDH, MEK1, and ARID1A. Each is linked with KIAA0040 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA0040-to-partner and partner-to-KIAA0040 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by KIAA0040-low versus KIAA0040-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0040→partner) and Y-score (partner→KIAA0040) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.614	+3.000	.047	.037	3	1
UCEC	MEK1 →	+0.491	+3.000	.020	.036	3	1
UCEC	ARID1A →	-0.220	-2.992	.037	.036	3	1
UCEC	ATM →	-0.817	-3.000	.001	.037	3	1
UCEC	4E-BP1 →	+0.600	+3.029	<.001	.018	3	1
UCEC	p62 Lck ligand →	+0.515	+3.000	.006	.037	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

GAPDH by KIAA0040 expression — UCEC

Explore this box plot interactively →