KIAA0040

Across TCGA cell cohorts, KIAA0040 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,125 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KIAA0040-associated GO terms across cancer lineages are Keratinocyte development, Cytotoxic T cell degranulation, and Bundle of His cell-Purkinje myocyte adhesion involved in cell communication. Each is linked with KIAA0040 in more than 10 cancer types. Because this analysis shows association rather than direction, both KIAA0040-to-partner and partner-to-KIAA0040 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Keratinocyte development grouped by KIAA0040-low versus KIAA0040-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0040→partner) and Y-score (partner→KIAA0040) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Keratinocyte development →	-0.837	-1.367	.001	.002	3	11
STOMACH	Cytotoxic T cell degranulation →	+0.363	+2.805	<.001	<.001	3	11
BLOOD_Lymphoma	Bundle of His cell-Purkinje myocyte adhesion involved in cell communication →	+1.054	+1.817	.001	.002	3	10
LARGE_INTESTINE	Negative regulation of supramolecular fiber organization →	+0.078	+1.390	<.001	<.001	3	9
URINARY_TRACT	Desmosome assembly →	+0.312	+3.359	<.001	<.001	3	9
OVARY	Cell-cell adhesion mediated by cadherin →	+0.203	+2.365	.002	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,125 associations by consensus.

Keratinocyte development by KIAA0040 expression — BLOOD_Leukemia

Explore this box plot interactively →