KHNYN

Across TCGA patient cohorts, KHNYN protein abundance is significantly associated with the RNA expression of many other genes, with 6,486 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KHNYN-associated genes across cancer lineages are HOMEZ, FKBP3, and GMPR2. Each is linked with KHNYN in more than 5 cancer types. Because this analysis shows association rather than direction, both KHNYN-to-partner and partner-to-KHNYN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KHNYN versus HOMEZ in LSCC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KHNYN→partner) and Y-score (partner→KHNYN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HOMEZ →	+0.525	+0.201	<.001	.001	3	6
LSCC	FKBP3 →	+0.518	+0.218	<.001	.001	3	5
BRCA	GMPR2 →	+0.421	+0.282	<.001	<.001	3	5
UCEC	C14orf119 →	+0.568	+0.118	<.001	.009	3	5
LSCC	JKAMP →	+0.371	+0.277	<.001	<.001	3	5
UCEC	HECTD1 →	+0.595	+0.248	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,486 associations by consensus.

KHNYN vs HOMEZ — LSCC

Explore this scatter interactively →