KHDRBS3

Across TCGA patient cohorts, KHDRBS3 mutation is significantly associated with the RNA expression of many other genes, with 2,398 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KHDRBS3-associated genes across cancer lineages are RAB28P3, PHKG1P2, and PGAM1P1. Each is linked with KHDRBS3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KHDRBS3-to-partner and partner-to-KHDRBS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAB28P3 grouped by KHDRBS3-low versus KHDRBS3-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KHDRBS3→partner) and Y-score (partner→KHDRBS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RAB28P3 →	+0.142	+4.297	.009	.009	3	2
COAD	PHKG1P2 →	+0.081	+6.409	<.001	<.001	3	2
COAD	PGAM1P1 →	+0.112	+4.893	<.001	.005	3	2
COAD	HSPD1P18 →	+0.395	+4.870	<.001	.002	3	2
UCEC	XRCC6 →	+0.478	+3.639	<.001	.001	3	2
UCEC	NUFIP1P1 →	+0.119	+2.419	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,398 associations by consensus.

RAB28P3 by KHDRBS3 expression — LUSC

Explore this box plot interactively →