KHDRBS3

Across TCGA pan-cancer cohorts, KHDRBS3 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of KHDRBS3’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where KHDRBS3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KHDRBS3 is over-expressed in tumor, although a few such as BRCA and BLCA show the opposite, repressed pattern.

KIRP, COAD, and LIHC are the cancer types where KHDRBS3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KHDRBS3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	IV	+0.964	<.001	9	view →
COAD	All	IV	+1.011	.003	7	view →
LIHC	Male	All	+0.922	<.001	7	view →
BRCA	All	III,IV	−0.588	<.001	6	view →
READ	Male	All	+0.996	.001	5	view →
BLCA	All	All	−0.830	.011	4	view →
LUSC	All	All	−0.467	.008	2	view →
ESCA	Female	All	−0.733	.022	1	view →
THCA	Male	All	+0.354	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

KHDRBS3–KIRP

Open the KIRP breakdown →