KHDRBS3

Across TCGA cell cohorts, KHDRBS3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,532 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KHDRBS3-associated GO terms across cancer lineages are Transcription elongation by RNA polymerase II, Spliceosomal tri-snRNP complex assembly, and Presynaptic active zone organization. Each is linked with KHDRBS3 in more than 9 cancer types. Because this analysis shows association rather than direction, both KHDRBS3-to-partner and partner-to-KHDRBS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription elongation by RNA polymerase II grouped by KHDRBS3-low versus KHDRBS3-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KHDRBS3→partner) and Y-score (partner→KHDRBS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Transcription elongation by RNA polymerase II →	+0.053	+1.404	.007	.001	3	10
SOFT_TISSUE	Spliceosomal tri-snRNP complex assembly →	+0.085	+2.055	<.001	<.001	3	7
OESOPHAGUS	Presynaptic active zone organization →	-0.167	-1.093	.004	.008	3	7
UPPER_AERODIGESTIVE_TRACT	Protein-DNA complex organization →	+0.054	+0.886	.001	.004	3	7
OVARY	Membrane depolarization during action potential →	-0.148	-1.662	<.001	.004	3	7
SKIN	Regulation of synaptic vesicle priming →	+0.045	+1.026	.002	.008	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,532 associations by consensus.

Transcription elongation by RNA polymerase II by KHDRBS3 expression — KIDNEY

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