KDM3A

Across TCGA cell cohorts, KDM3A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,553 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KDM3A-associated GO terms across cancer lineages are Formaldehyde metabolic process, Peptidyl-serine phosphorylation, and Mitotic cytokinesis. Each is linked with KDM3A in more than 17 cancer types. Because this analysis shows association rather than direction, both KDM3A-to-partner and partner-to-KDM3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Formaldehyde metabolic process grouped by KDM3A-low versus KDM3A-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM3A→partner) and Y-score (partner→KDM3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Formaldehyde metabolic process →	+0.170	+0.858	<.001	<.001	3	18
LUNG_NSCLC_LUAD	Peptidyl-serine phosphorylation →	+0.071	+0.761	<.001	<.001	2	13
STOMACH	Mitotic cytokinesis →	+0.088	+0.962	<.001	<.001	3	12
LARGE_INTESTINE	Insulin-like growth factor receptor signaling pathway →	+0.101	+0.708	<.001	<.001	3	12
STOMACH	Endosomal transport →	+0.059	+0.752	.003	<.001	3	11
LUNG_SCLC	Regulation of cilium assembly →	+0.049	+0.485	<.001	.008	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,553 associations by consensus.

Formaldehyde metabolic process by KDM3A expression — OESOPHAGUS

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