KDM2A

Across TCGA cell cohorts, KDM2A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,922 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KDM2A-associated GO terms across cancer lineages are Regulation of mRNA splicing, via spliceosome, Regulation of alternative mRNA splicing, via spliceosome, and Endosomal transport. Each is linked with KDM2A in more than 17 cancer types. Because this analysis shows association rather than direction, both KDM2A-to-partner and partner-to-KDM2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA splicing, via spliceosome grouped by KDM2A-low versus KDM2A-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM2A→partner) and Y-score (partner→KDM2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of mRNA splicing, via spliceosome →	+0.095	+0.833	<.001	<.001	3	18
BONE	Regulation of alternative mRNA splicing, via spliceosome →	+0.117	+1.175	<.001	.001	3	17
STOMACH	Endosomal transport →	+0.095	+1.015	<.001	<.001	3	16
STOMACH	Regulation of mRNA processing →	+0.100	+0.974	<.001	<.001	3	16
STOMACH	Positive regulation of TORC2 signaling →	+0.106	+0.773	<.001	<.001	3	15
OESOPHAGUS	Regulation of DNA-templated transcription initiation →	+0.093	+1.207	.001	.003	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,922 associations by consensus.

Regulation of mRNA splicing, via spliceosome by KDM2A expression — BLOOD_Lymphoma

Explore this box plot interactively →