KCTD18

Across TCGA patient cohorts, KCTD18 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,009 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KCTD18-associated proteins across cancer lineages are UBE2J1, NIF3L1, and DNAJC1. Each is linked with KCTD18 in more than 5 cancer types. Because this analysis shows association rather than direction, both KCTD18-to-partner and partner-to-KCTD18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCTD18 versus UBE2J1 in LSCC, with a Pearson correlation of -0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD18→partner) and Y-score (partner→KCTD18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UBE2J1 →	-0.479	-0.372	<.001	<.001	3	6
PDAC	NIF3L1 →	+0.379	+0.350	<.001	<.001	3	6
LUAD	DNAJC1 →	-0.479	-0.382	<.001	<.001	3	5
PDAC	FKBP11 →	-0.661	-0.275	.001	.001	3	5
LSCC	SPCS3 →	-0.471	-0.411	<.001	<.001	3	5
LSCC	SPR →	+0.440	+0.480	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,009 associations by consensus.

KCTD18 vs UBE2J1 — LSCC

Explore this scatter interactively →