KCTD18

Across TCGA patient cohorts, KCTD18 protein abundance is significantly associated with the RNA expression of many other genes, with 6,743 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KCTD18-associated genes across cancer lineages are HLF, TRPV4, and TANC1. Each is linked with KCTD18 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCTD18-to-partner and partner-to-KCTD18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCTD18 versus HLF in LUAD, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD18→partner) and Y-score (partner→KCTD18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HLF →	+1.370	+0.262	<.001	<.001	3	3
HNSC	TRPV4 →	+0.901	+0.283	<.001	<.001	3	3
HNSC	TANC1 →	+0.391	+0.186	<.001	.004	3	3
LSCC	CHMP3 →	+0.328	+0.222	<.001	.007	3	3
LUAD	ACVR2A →	+0.358	+0.170	<.001	<.001	3	3
LSCC	CEP20 →	+0.627	+0.223	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,743 associations by consensus.

KCTD18 vs HLF — LUAD

Explore this scatter interactively →