KCTD18

Across TCGA cell cohorts, KCTD18 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,506 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCTD18-associated GO terms across cancer lineages are Golgi vesicle transport, Sperm motility, and Process utilizing autophagic mechanism. Each is linked with KCTD18 in more than 15 cancer types. Because this analysis shows association rather than direction, both KCTD18-to-partner and partner-to-KCTD18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by KCTD18-low versus KCTD18-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD18→partner) and Y-score (partner→KCTD18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.063	+0.729	.004	.002	3	16
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.112	-0.713	.001	.001	3	15
PANCREAS	Process utilizing autophagic mechanism →	+0.058	+0.754	.001	.001	3	15
PANCREAS	Autophagy →	+0.058	+0.754	.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.112	-0.713	.001	.001	3	15
BLOOD_Myeloma	Macroautophagy →	+0.060	+0.866	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,506 associations by consensus.

Golgi vesicle transport by KCTD18 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →