Across TCGA patient cohorts, KCNU1 mutation is significantly associated with the RNA expression of many other genes, with 5,229 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNU1-associated genes across cancer lineages are RCC1, RFC5, and NEIL3. Each is linked with KCNU1 in more than 4 cancer types. Because this analysis shows association rather than direction, both KCNU1-to-partner and partner-to-KCNU1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNU1→partner) and Y-score (partner→KCNU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RCC1 →	+0.472	+2.010	<.001	<.001	3	5
STAD	RFC5 →	+0.592	+3.484	<.001	.002	3	5
UCEC	NEIL3 →	+0.539	+3.191	<.001	<.001	3	5
LUAD	NCAPH →	+0.709	+2.201	.001	<.001	3	5
LUAD	ZWINT →	+0.735	+1.596	<.001	.006	3	5
LUAD	CEP55 →	+0.776	+2.602	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,229 associations by consensus.

Exploration

KCNU1 survival (RNA) · tumor vs normal (RNA) · all KCNU1 data types