Across TCGA patient cohorts, KCNQ5 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,611 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KCNQ5-associated proteins across cancer lineages are CACNA2D1, TJP3_S203, and SMARCA2_S329. Each is linked with KCNQ5 in more than 5 cancer types. Because this analysis shows association rather than direction, both KCNQ5-to-partner and partner-to-KCNQ5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNQ5→partner) and Y-score (partner→KCNQ5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CACNA2D1 →	+0.773	+1.690	<.001	<.001	3	6
HNSC	TJP3_S203 →	-0.621	-0.803	.001	.001	3	5
OV	SMARCA2_S329 →	+0.761	+0.770	.001	.001	3	4
UCEC	RAB12 →	+0.333	+0.459	<.001	.003	3	4
COAD	RCN3 →	+0.492	+0.180	<.001	.002	3	4
UCEC	SHTN1 →	-0.369	-0.446	.004	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,611 associations by consensus.

Exploration

KCNQ5 survival (RNA) · tumor vs normal (RNA) · all KCNQ5 data types