Across TCGA patient cohorts, KCNQ5 protein abundance is significantly associated with the RNA expression of many other genes, with 2,306 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCNQ5-associated genes across cancer lineages are F13A1, CYTH4, and SUSD6. Each is linked with KCNQ5 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNQ5-to-partner and partner-to-KCNQ5 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNQ5→partner) and Y-score (partner→KCNQ5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	F13A1 →	+2.062	+0.525	<.001	.004	3	3
GBM	CYTH4 →	+0.763	+0.536	.001	<.001	3	2
BRCA	SUSD6 →	+0.610	+0.878	.002	.001	3	2
LSCC	GID8 →	-0.621	-0.683	<.001	.008	3	2
LSCC	KLHDC4 →	-0.506	-0.898	.005	.003	3	2
GBM	CD33 →	+0.541	+0.428	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,306 associations by consensus.

Exploration

KCNQ5 survival (RNA) · tumor vs normal (RNA) · all KCNQ5 data types