Across TCGA patient cohorts, KCNQ5 mutation is significantly associated with the RNA expression of many other genes, with 4,137 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNQ5-associated genes across cancer lineages are NCAPD3, KPNB1, and PDS5A. Each is linked with KCNQ5 in more than 5 cancer types. Because this analysis shows association rather than direction, both KCNQ5-to-partner and partner-to-KCNQ5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNQ5→partner) and Y-score (partner→KCNQ5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	NCAPD3 →	+0.618	+2.355	.001	.003	3	6
STAD	KPNB1 →	+0.349	+2.647	.005	.004	3	5
UCEC	PDS5A →	+0.386	+1.224	.001	.005	3	5
UCEC	SGO1 →	+0.429	+2.364	.003	<.001	3	5
STAD	LARP1B →	+0.540	+3.856	<.001	<.001	3	5
UCEC	SLBP →	+0.388	+2.238	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,137 associations by consensus.

Exploration

KCNQ5 survival (RNA) · tumor vs normal (RNA) · all KCNQ5 data types