Across TCGA cell cohorts, KCNQ5 mutation is significantly associated with the RNA expression of many other genes, with 734 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNQ5-associated genes across cancer lineages are SNU13, PIK3C3, and CLUL1. Each is linked with KCNQ5 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNQ5-to-partner and partner-to-KCNQ5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNQ5→partner) and Y-score (partner→KCNQ5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SNU13 →	+0.541	+2.743	<.001	.001	3	2
LARGE_INTESTINE	PIK3C3 →	+0.727	+2.743	<.001	.001	3	2
LARGE_INTESTINE	CLUL1 →	+0.287	+2.526	.002	.002	3	2
BLOOD_Myeloma	PZP →	+0.036	+4.807	<.001	.006	3	1
SKIN	RBX1 →	+0.486	+3.137	.001	.007	2	2
SKIN	DHX35 →	-0.494	-3.192	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 734 associations by consensus.

Exploration

KCNQ5 survival (RNA) · tumor vs normal (RNA) · all KCNQ5 data types