KCNQ1DN

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KCNQ1DN RNA expression is significantly associated with the protein abundance of many other proteins, with 9,233 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCNQ1DN-associated proteins across cancer lineages are ZC2HC1A, USP24_S1925, and RGS14_S203. Each is linked with KCNQ1DN in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNQ1DN-to-partner and partner-to-KCNQ1DN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNQ1DN versus ZC2HC1A in GBM, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNQ1DN→partner) and Y-score (partner→KCNQ1DN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMZC2HC1A →+0.306+0.404<.001<.00133
GBMUSP24_S1925 →-0.483-0.374.001.00332
GBMRGS14_S203 →+0.380+0.353.005.00532
CCRCCCADM3 →+1.685+0.096<.001<.00132
GBMDHFR →-0.496-0.358.001.00832
GBMDLG4_S295 →+0.754+0.327<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,233 associations by consensus.

KCNQ1DN vs ZC2HC1A — GBM

Per-sample scatter of KCNQ1DN vs ZC2HC1A in GBM (Pearson r = 0.44).

Explore this scatter interactively →

Exploration