KCNQ1DN

Across TCGA pan-cancer cohorts, KCNQ1DN RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated KCNQ1DN data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher KCNQ1DN RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KCNQ1DN expression acts as an unfavorable survival marker, although some lineages such as SARC and BRCA show a favorable association.

ACC, OV, and LUAD are the cancer types where KCNQ1DN RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.197	0.776	<.001	68	view →
OV	DFS	Median	IV	0.303	0.597	<.001	28	view →
LUAD	DFS	Tertile	IV	0.220	0.691	.016	24	view →
COAD	OS	Tertile	IV	0.183	0.670	.003	18	view →
LIHC	OS	Tertile	All	0.478	0.803	.001	18	view →
SARC	DFS	Tertile	All	0.716	0.562	.003	16	view →
THCA	OS	Tertile	II,III,IV	0.910	0.977	.014	15	view →
KIRC	OS	Median	All	0.559	0.680	.008	11	view →
THYM	OS	Quartile	All	0.872	1.000	.019	7	view →
BRCA	DFS	Quartile	All	0.685	0.476	.012	6	view →
PAAD	DFS	Tertile	II,III,IV	0.388	0.275	.039	6	view →
CESC	OS	Median	All	0.872	0.751	.018	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

KCNQ1DN–ACC (OS)

Open the ACC breakdown →