KCNMB1

Across TCGA patient cohorts, KCNMB1 mutation is significantly associated with the RNA expression of many other genes, with 151 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KCNMB1-associated genes across cancer lineages are OR1E3, MIR1255B2, and MTND6P8. Each is linked with KCNMB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNMB1-to-partner and partner-to-KCNMB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1E3 grouped by KCNMB1-low versus KCNMB1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNMB1→partner) and Y-score (partner→KCNMB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OR1E3 →	+0.030	+3.767	.001	.003	3	2
HNSC	MIR1255B2 →	+0.310	+4.146	<.001	.008	3	2
LUAD	MTND6P8 →	+0.036	+4.263	.002	.007	3	2
SKCM	RNU6-13P →	+0.174	+3.372	<.001	.005	3	2
CESC	NEUROD6 →	+0.021	+5.812	<.001	.003	3	1
CESC	PABPC1L2A →	+0.043	+5.669	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 151 associations by consensus.

OR1E3 by KCNMB1 expression — HNSC

Explore this box plot interactively →