KCNK6

Across TCGA cell cohorts, KCNK6 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible KCNK6-associated genes across cancer lineages are CST9L, TPPP2, and PROKR1. Each is linked with KCNK6 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNK6-to-partner and partner-to-KCNK6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CST9L grouped by KCNK6-low versus KCNK6-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK6→partner) and Y-score (partner→KCNK6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CST9L →	+0.042	+5.369	<.001	.004	3	1
SOFT_TISSUE	TPPP2 →	+0.168	+4.930	<.001	.008	3	1
OVARY	PROKR1 →	+0.074	+3.866	<.001	.002	3	1
OVARY	GPR148 →	+0.042	+3.095	<.001	.009	3	1
OVARY	MPPED1 →	+0.143	+3.473	<.001	.008	3	1
OVARY	DLGAP2 →	+0.367	+3.714	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

CST9L by KCNK6 expression — SOFT_TISSUE

Explore this box plot interactively →