Across TCGA patient cohorts, KCNK4 mutation is significantly associated with the RNA expression of many other genes, with 1,244 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNK4-associated genes across cancer lineages are H2AB2, PTP4A1P6, and MIR7702. Each is linked with KCNK4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNK4-to-partner and partner-to-KCNK4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK4→partner) and Y-score (partner→KCNK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	H2AB2 →	+0.049	+7.057	<.001	.009	3	2
SKCM	PTP4A1P6 →	+0.261	+3.578	<.001	.007	3	2
UCEC	MIR7702 →	+0.263	+4.475	<.001	.003	3	2
COAD	LYPLA1P1 →	+0.211	+4.824	<.001	.002	3	2
COAD	PARK7P2 →	+0.262	+3.383	<.001	.002	3	2
COAD	RN7SL93P →	+0.328	+3.408	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,244 associations by consensus.

Exploration

KCNK4 survival (RNA) · tumor vs normal (RNA) · all KCNK4 data types