KCNK16

Across TCGA patient cohorts, KCNK16 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,380 significant associations in total. THCA shows the largest number of these associations.

The most reproducible KCNK16-associated GO terms across cancer lineages are Regulation of hormone secretion, Positive regulation of double-strand break repair, and Transport along microtubule. Each is linked with KCNK16 in more than 10 cancer types. Because this analysis shows association rather than direction, both KCNK16-to-partner and partner-to-KCNK16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of hormone secretion grouped by KCNK16-low versus KCNK16-high in PAAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK16→partner) and Y-score (partner→KCNK16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PAAD	Regulation of hormone secretion →	+0.026	+2.439	<.001	<.001	3	10
SCLC	Positive regulation of double-strand break repair →	+0.052	+1.529	.002	<.001	3	9
LAML	Transport along microtubule →	+0.024	+0.446	<.001	<.001	3	9
STAD	Regulation of canonical Wnt signaling pathway →	+0.051	+0.272	<.001	<.001	3	9
COAD	Peptidyl-lysine modification →	+0.024	+0.032	<.001	.004	3	9
STAD	Autophagy of mitochondrion →	+0.067	+0.251	<.001	.003	1	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,380 associations by consensus.

Regulation of hormone secretion by KCNK16 expression — PAAD

Explore this box plot interactively →